AltrixBio was founded in 2019 to further develop their idea of “Surgery in a Pill”, a platform to deliver drugs to the gastrointestinal (GI) tract. They teamed up with Doctor’s from Brigham and Women’s Hospital, Harvard Medical School and MIT who were fascinated by the rapid resolution of Type 2 Diabetes and weight loss that is seen in patients that undergo gastric bypass surgery. This work led to the development of LuCiÔ, a repurposed pill that adheres to the GI track. In pre-clinical proof-of-concept models, it has been shown to modulate nutrient contact with the bowl mucosa and lower the glucose response.  They are currently working on getting a usable formulation of the drug to start “Pre-IND” meetings with the FDA. They hope to start clinical trials by the end of 2020. They have raised $1.5M in fundraising since starting as Nest.Bio Labs. 

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